Acid-base bifunctional catalytic surfaces for nucleophilic addition reactions

作者：Motokura Ken; Tada Mizuki; Iwasawa Yasuhiro^*

来源：Chemistry-An Asian Journal, 2008, 3(8-9): 1230-1236.

DOI：10.1002/asia.200800126

• aldol reaction
• bifunctional catalysis
• C-C coupling
• nucleophilic addition
• supported catalysts

This article illustrates the modification of oxide surfaces with organic amine functional groups to create acid-base bifunctional catalysts, summarizing our previous reports and also presenting new data. Immobilization of organic amines as bases on inorganic solid-acid surfaces afforded highly active acid-base bifunctional catalysts, which enabled various organic transformations including C-C coupling reactions, though these reactions did not proceed with either the homogeneous amine precursors or the acidic supports alone. Spectroscopic characterization, such as by solid-state MAS NMR and FTIR, revealed not only the interactions between acidic and basic sites but also bifunctional catalytic reaction mechanisms.

• 出版日期2008