Development of a Sensor for Specific Protein Detection by the Example of Norovirus Capsid Protein

作者：Paessler Sandra; Vonau Winfried; Mertig Michael; Henseleit Anja; Quenzel Philipp; Boschke Elke; Lange Ada; Jaeger Katrin; Rohayem Jacques; Pohl Andrea; Opitz Joerg; Haufe Nora

来源：Technisches Messen, 2013, 80(5): 155-161.

DOI：10.1524/teme.2013.0025

• Aptamer
• thrombin
• surface plasmon resonance
• electrochemical impedance spectroscopy
• SELEX
• norovirus

The results of the development of molecular based principles for the detection of proteins are presented. These are essentially based on the evidence of the specific interaction of aptamers with proteins by means of impedimetric measurement methods and surface plasmon resonance spectroscopy. Additionally, the recombinant expression of the capsid proteins of noroviruses and their use for the selection of norovirus specific aptamers are shown.

• 出版日期2013