Antimicrobial activity of some synthesized glucopyranosyl-pyrimidine carbonitrile and fused pyrimidine systems

作者:Sayed Hayam H; Abbas Hebat Allah S; Morsi Eman M H; Amr Abd El Galil E*; Abdelwahad Nayera A M
来源:Acta Pharmaceutica, 2010, 60(4): 479-491.
DOI:10.2478/v10007-010-0033-8

摘要

3-Amino-5-(4-chlorophenylamino)-4-cyanofuran-2-carboxamide (2) was used as the key molecule for preparation of various furopyrimidines 3-9 and formation of spiro-cycloalkane furopyrimidines 10, 11. Also, poly fused heterocyclic compounds 13-17 were prepared from compound 2. The synthesized compounds were screened for their antimicrobial activity.

  • 出版日期2010-12