Diastereocontrol in [4 4]-photocycloadditions of pyran-2-ones: effect of ring substituents and chiral ketal

作者：Li Lei; Bender John A; West F G^*

来源：Tetrahedron Letters, 2009, 50(11): 1188-1192.

DOI：10.1016/j.tetlet.2008.12.117

4-Mesyloxypyran-2-ones joined to furan by a three-carbon linker undergo intramolecular-crossed [4 4]-photocycloaddition with high or complete selectivity for the exo cycloadcluct. When a C(2)-symmetric ketal was present on the tether adjacent to the pyranone ring, moderate levels of asymmetric induction were obtained.

• 出版日期2009-3-18