Association of RETN and CAP1 SNPs, Expression and Serum Resistin Levels with Breast Cancer in Mexican Women

作者：Munoz Palomeque Alejandrina; Angel Guerrero Ramirez Miguel; Ariadna Rubio Chavez Lidia; Carlos Rosales Gomez Roberto; Guadalupe Lopez Cardona Maria; Hugo Barajas Avila Victor; Delgadillo Barrera Alfredo; Carlos Canton Romero Juan; Montoya Fuentes Hector; Arcelia Garcia Cobian Teresa; Andrea Gutierrez Rubio Susan

来源：Genetic Testing and Molecular Biomarkers, 2018, 22(4): 209-217.

DOI：10.1089/gtmb.2017.0212

• breast cancer
• CAP1
• Mexican women
• resistin
• RETN

Background: Breast cancer is the most common cancer in women worldwide. Approximately 70% of female breast cancer patients have a body mass index (BMI) >25. In obesity, adipose tissue secretes additional resistin, which prompts a proinflammatory effect through its action on adenylate cyclase-associated protein 1 (CAP1). Several studies have associated the RETN gene single nucleotide polymorphism (SNP) rs1862513 (-420C

• 出版日期2018-4