Bone Mineral Density Changes in the Hip and Spine of Men and Women 1-Year After Primary Cemented Total Knee Arthroplasty: Prospective Cohort Study

作者：Beaupre Lauren A^*; Rezansoff Alexander; Clark Marcia; Jen Ho; Lambert Robert G; Majumdar Sumit

来源：Journal of Arthroplasty, 2015, 30(12): 2185-2189.

DOI：10.1016/j.arth.2015.06.026

• total knee arthroplasty
• bone mineral density
• fracture risk
• osteoporosis
• risk adjustment

This study evaluated age-and sex-adjusted changes in total hip and spine bone mineral density (BMD) within 1 year of total knee arthroplasty (TKA) using a prospective, longitudinal cohort with a one-year follow-up. Preoperatively, subjects underwent routine bone mineral densitometry of their hip and spine, which was repeated 12 months postoperatively. Of 108 subjects, 97 (90%) completed BMD testing. Total hip BMD decreased significantly over time (1.80% change, P < 0.001) with females losing more than males (P < 0.001). The pattern was similar, but attenuated in the spine. Subjects undergoing primary cemented TKA had significant bone loss in the hip within 12 months, beyond that expected with age.

• 出版日期2015-12