A path forward for the chlamydial virulence factor CPAF

作者：Conrad Turner A; Yang Zhangsheng; Ojcius David; Zhong Guangming^*

来源：Microbes and Infection, 2013, 15(14-15): 1026-1032.

DOI：10.1016/j.micinf.2013.09.008

• CPAF
• Substrates
• Chlamydial virulence factors and pathogenesis

CPAF is a conserved and secreted protease from obligate intracellular bacteria of the order Chlamydiales. Recently, it was demonstrated that most of its host targets are an artifact of inaccurate methods. This review aims to summarize key features of CPAF and propose new approaches for evaluating its role in chlamydial pathogenesis.

• 出版日期2013-12