Analytical Methods for Metformin Estimation

作者：Patel Durgawati; Kumar Puspendra; Sharma Swapnil^*; Dwivedi Jaya

来源：Critical Reviews in Analytical Chemistry, 2017, 47(5): 405-417.

DOI：10.1080/10408347.2017.1304200

• Metformin
• analytical methods
• pharmaceutical formulations
• biological matrices

Metformin is a widely prescribed oral anti-hyperglycemic agent used in the management of non-insulin dependent diabetes mellitus (NIDDM) or type II diabetes. This article accentuates various analytical methods viz. HPLC, HPTLC, spectrophotometric, electrochemical, capillary electrophoresis and LC-MS for the estimation of metformin in pharmaceutical formulations and in biological matrices.

• 出版日期2017