A New Trinor-guaiane Sesquiterpene from an Indonesian Soft Coral Anthelia sp.

作者：Hanif Novriyandi^*; Murni Anggia; Yamauchi Marie; Higashi Masahiro; Tanaka Junichi

来源：Natural Product Communications, 2015, 10(11): 1907-1910.

DOI：10.1177/1934578x1501001124

• Soft coral
• Anthelia sp.
• Trinor-guaiane
• Sesquiterpene
• Cytotoxicity
• Indonesia

A new trinor-guaiane sesquiterpene has been isolated from an Indonesian soft coral Anthelia sp. The planar structure, possessing an octahydroazulene skeleton, and relative stereochemistry were established by analyzing 1D and 2D NMR data, including NOB experiments. Its absolute stereochemistry was elucidated to be IS, 48, 7R, and lOR by comparing observed and calculated optical rotation values. The new compound showed weak cytotoxicity against NBT-T2 cells.

• 出版日期2015-11