A Novel Approach for the Synthesis of Furopyrimidine and Oxobenzofuran Derivatives

作者:Bayat Mohammad*; Shiraz Nader Zabarjad; Hosseini Seyyed Hajar
来源:Helvetica Chimica Acta, 2010, 93(11): 2189-2193.
DOI:10.1002/hlca.201000029

摘要

A novel, efficient one pot approach for the synthesis of furopyrimidine and oxobenzofuran derivatives 4 by a multicomponent reaction of an isocyanide, an aldehyde, and a CH-acid compound in CH2Cl2 is reported (Scheme I and Table) The reactions were completed after 20 h at room temperature This method has the advantages of high yields, simple methodology, and easy workup

  • 出版日期2010