Size-controlled long-circulating PICsome as a ruler to measure critical cut-off disposition size into normal and tumor tissues

作者：Anraku Yasutaka; Kishimura Akihiro^*; Kobayashi Atsushi; Oba Makoto; Kataoka Kazunori

来源：Chemical communications, 2011, 47(21): 6054-6056.

DOI：10.1039/c1cc11465d

Selective disposition of nanocarriers into target tissue is an essential issue in drug delivery. Critical size of nanocarriers (similar to 150 nm) discriminating the permeability into normal and tumor tissues was determined by the use of size-tunable, polyion complex hollow vesicles (PICsome) as a ruler.

• 出版日期2011