ANTIOXIDANT ACTIVITY OF COVOLVULUS HYSTRIX VAHL AND ITS CHEMICAL CONSTITUENTS

作者：Donia Abd El Raheim Mohammed^*; Alqasoumi Saleh Ibrahim; Awaad Amani Shafeek; Cracker Lyle

来源：Pakistan Journal of Pharmaceutical Sciences, 2011, 24(2): 143-147.

• Antioxidant activity
• Convolvulus hystrix
• flavonoids
• ferulic acid
• total phenolics

Total alcohol and successive extracts (diethyl ether, chloroform, ethyl acetate and n-butanol) of Covolvulus hystrix Vahl were screened for their antioxidant activity using free radical 2-2- diphenyl-1-picrylhydrazyl (DPPH) and Trolox as reference substance. The tested extracts showed variable antioxidant activities. The highest antioxidant activity was achieved in total alcohol (48.32%) followed by ethyl acetate (37.8 %) and n-butanol (32.96 %) extracts. From the ethyl acetate extract four compounds were isolated and identified as quercetin, quercetin 3-0-rutinoside and quercetin-7-O-rhamnoside in addition to ferulic acid using different spectroscopic analysis such as, (HNIVIR)-H-1, (CNMR)-C-13, COSY, HMBC and HMQC.

• 出版日期2011-4