Matched optical quality comparison of 3-year results of PRK-MMC and phakic IOL implantation in the correction of high myopia

作者：Miraftab M; Hashemi H^*; Asgari S

来源：Eye, 2015, 29(7): 926-931.

DOI：10.1038/eye.2015.71

Aims To compare 3-year results of PRK-MMC and phakic intraocular lens (PIOL) implantation in patients with >8.0 diopters (D) of myopia.
Methods This study was conducted as a non-randomized clinical trial on 23 eyes treated with PIOL (Artiflex; group A) and 23 eyes treated with PRK-MMC (group B). This report compares 3-year treatment results in these two groups.
Results At 3 years after surgery, uncorrected visual acuity was 0.02 +/- 0.06 LogMAR in group A and 0.04 +/- 0.07 LogMAR in group B (P = 0.639). Mean best corrected visual acuity in group A (0.004 +/- 0.02) was better than group B (0.03 +/- 0.07 LogMAR) (P = 0.035). Mean manifest refraction spherical equivalent was -0.16 +/- 0.21 and -0.09 +/- 0.20D (P = 0.190), respectively. Mesopic contrast sensitivity (CS) in the spatial frequency of three cycle/degree (CS3) significantly decreased in both groups, but the reduction was significantly higher in group B (P = 0.024). CS6 decreased significantly only in group B (P = 0.019). Changes in CS12 and CS18 showed no significant inter-group difference. In group A, the increase in C6 trefoil (0.16 +/- 0.18 mu m, P = 0.003) and reduction in spherical aberration (SA; 0.16 +/- 0.08 mu m, P < 0.001) were statistically significant. In group B, the reduction in vertical coma (P = 0.052), and increases in horizontal coma (P = 0.044), coma (P < 0.001), SA (P < 0.001), and total higher order aberrations (P < 0.001) were significant after surgery.
Conclusion Based on 3-year results, PIOL implantation is a better choice than PRK-MMC for treating patients with >8.0D myopia. However, for patients with an inadequate aqueous depth, PRK-MMC can be an acceptable treatment option with a potential for decreased quality of vision.

• 出版日期2015-7