Acquired factor V inhibitors: a systematic review

作者:Franchini Massimo*; Lippi Giuseppe
来源:Journal of Thrombosis and Thrombolysis, 2011, 31(4): 449-457.
DOI:10.1007/s11239-010-0529-6

摘要

The occurrence of an inhibitor against coagulation factor V (FV) is a rare but challenging condition, which may span from asymptomatic laboratory abnormalities to potentially life-threatening bleeding. The onset of FV inhibitors has been associated most frequently in the past with the patients' exposure to topical bovine thrombin administered during surgery procedures. However, since this preparation is no longer used, in this systematic review we have only focused on non-bovine thrombin-related FV inhibitor cases.

  • 出版日期2011-5