Azodioxy-carbonyl compounds by oxidation of cyclic imines with m-CPBA

作者：Perrone Serena; Pilati Tullio; Rosato Francesca; Salomone Antonio; Videtta Valeria; Troisi Luigino^*

来源：Tetrahedron, 2011, 67(11): 2090-2095.

DOI：10.1016/j.tet.2011.01.054

• Imines
• Oxaziridines
• Azodioxy
• Oximes
• C-Nitroso compounds

This article reports a simple and efficient synthesis of C-nitroso compounds (azodioxy esters or ketones and oximes) through a double oxidation of cyclic imines (4,5-dihydrooxazoles and 3,4-dihydro-2H-pyrroles) with m-CPBA. C-Nitroso derivatives seem to be potential donors of nitric oxide, one of the most powerful biological messenger. Published by Elsevier Ltd.

• 出版日期2011-3-18