Anatomising proton NMR spectra with pure shift 2D J-spectroscopy: A cautionary tale

作者：Kiraly Peter; Foroozandeh Mohammadali; Nilsson Mathias; Morris Gareth A^*

来源：Chemical Physics Letters, 2017, 683: 398-403.

DOI：10.1016/j.cplett.2017.01.031

• J-spectroscopy
• Pure shift
• PSYCHE
• 2DJ
• J-coupling

Analysis of proton NMR spectra has been a key tool in structure determination for over 60 years. A classic tool is 2D J-spectroscopy, but common problems are the difficulty of obtaining the absorption mode lineshapes needed for accurate results, and the need for a 45 degrees shear of the final 2D spectrum. A novel 2D NMR method is reported here that allows straightforward determination of homonuclear couplings, using a modified version of the PSYCHE method to suppress couplings in the direct dimension. The method illustrates the need for care when combining pure shift data acquisition with multiple pulse methods.

• 出版日期2017-9-1