Schistosome genomes: a wealth of information

作者:Webster Joanne P*; Oliviera Guilherme; Rollinson David; Gower Charlotte M
来源:Trends in Parasitology, 2010, 26(3): 103-106.
DOI:10.1016/j.pt.2009.12.006

摘要

The blood flukes Schistosoma japonicum and Schistosoma mansoni are the first major human platyhelminth pathogens to have their genome sequences published. The work of two large international consortia offers draft sequence information and detailed analyses presenting a wealth of information addressing, in particular, metabolic and signalling pathways, host-parasite interactions and potential new drug targets. We comment on these breakthroughs and their potential applications in the study and control of schistosomes.

  • 出版日期2010-3