Nanocrystalline hydroxyapatite enriched in selenite and manganese ions: physicochemical and antibacterial properties

作者：Kolmas Joanna^*; Groszyk Ewa; Piotrowska Urszula

来源：Nanoscale Research Letters, 2015, 10(1): 278.

DOI：10.1186/s11671-015-0989-x

• Nanocrystalline hydroxyapatite
• Selenite
• Manganese
• Physicochemical properties
• Infrared spectroscopy
• Powder diffractometry
• Nuclear magnetic resonance
• Antibacterial properties
• Biomaterials
• Bioceramics

In this work, we used the co-precipitation method to synthesize hydroxyapatite (Mn-SeO3-HA) containing both selenium IV (approximately 3.60 wt.%) and manganese II (approximately 0.29 wt.%). Pure hydroxyapatite (HA), hydroxyapatite-containing manganese (II) ions (Mn-HA), and hydroxyapatite-containing selenite ions alone (SeO3-HA), prepared with the same method, were used as reference materials. The structures and physicochemical properties of all the obtained samples were investigated. PXRD studies showed that the obtained materials were homogeneous and consisted of apatite phase. Introducing selenites into the hydroxyapatite crystals considerably affects the size and degree of ordering. Experiments with transmission electron microscopy (TEM) showed that Mn-SeO3-HA crystals are very small, needle-like, and tend to form agglomerates. Fourier transform infrared spectroscopy (FT-IR) and solid-state nuclear magnetic resonance (ssNMR) were used to analyze the structure of the obtained material. Preliminary microbiological tests showed that the material demonstrated antibacterial activity against Staphylococcus aureus, yet such properties were not confirmed regarding Escherichia coli.

• 出版日期2015-7-3