A convenient method for the synthesis of 2-[(5-benzyl-1,3-thiazol-2-yl)imino]-1,3-thiazolidin-4-one derivatives

作者：Ostapiuk Yuri V; Obushak Mykola D^*; Matiychuk Vasyl S; Naskrent Marek; Gzella Andrzej K

来源：Tetrahedron Letters, 2012, 53(5): 543-545.

DOI：10.1016/j.tetlet.2011.11.093

• Thiazole derivatives
• Thiazolidin-4-ones
• Thiocyanates
• Chloroacetamides
• Meerwein reaction

It was found that the reaction of 2-chloroacetamido/chloropropioamido-5-benzylthiazole with potassium thiocyanate gave, via rearrangement, 2-[(5-benzyl-1,3-thiazol-2-yl)imino]-1,3-thiazolidin-4-ones.

• 出版日期2012-2-1