A photoresponse-compensated parallel piezoresistive cantilever for cellular force measurements

作者:Jung Uijin G*; Kuwana Kenta; Ajiki Yoshiharu; Takahashi Hidetoshi; Kan Tetsuo; Takei Yusuke; Noda Kentaro; Iwase Eiji; Matsumoto Kiyoshi; Shimoyama Isao
来源:Journal of Micromechanics and Microengineering, 2013, 23(4): 045015.
DOI:10.1088/0960-1317/23/4/045015

摘要

This paper describes a parallel piezoresistive cantilever that is composed of a force-sensing cantilever in addition to a reference cantilever for photoresponse compensation. Piezoresistive cantilevers have been applied in many cellular mechanical measurement studies because of their high sensitivity, high time resolution and ease of handling. However, the electrical resistance changes in response to the excitation light of the fluorescence microscope, which affects the cell measurements. We measured the I-V characteristics of a piezoresistive layer. These photoresponses occurred due to the internal photoelectric effect. We canceled the photoresponses using the reference cantilever. This paper demonstrates compensation of the cantilever photoresponse under irradiation at different angles, wavelengths and light intensities. As a result, the photoresponse could be decreased by 87%.

  • 出版日期2013-4

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