A novel solvent-dependently bifunctional NIR absorptive and fluorescent ratiometric probe for detecting Fe3+/Cu2+ and its application in bioimaging

作者：Li, Shao; Zhang, Di^*; Xie, Xinyu; Ma, Saige; Liu, Yao; Xu, Zhanhui; Gao, Yanfeng; Ye, Yong

来源：Sensors and Actuators B: Chemical , 2016, 224: 661-667.

DOI：10.1016/j.snb.2015.10.086

• NIR
• Fluorescent probe
• Fe3+
• Cu2+
• Cyanine
• Rhodamine

A novel rhodamine-cyanine based probe LS1 was designed and synthesized, which can act as a bifunctional NIR ratiometric colorimetric and fluorescent probe for detecting Fe3+ and Cu2+ in solvent of MeOH/H2O and MeCN/H2O respectively. As expected, it exhibited high selectivity and sensitivity for detecting Fe3+ and Cu2+ over other commonly coexistent metal ions in their respective systems with a broad pH span. The detection limit was measured to be 0.737 mu M for Fe3' and 1.019 mu M for Cu2+. Furthermore, fluorescence imaging experiments of Cu2+ ions in living SH-SY5Y109 cells demonstrated its value of practical application in biological systems.

• 出版日期2016-3-1
• 单位河南省农业科学院; 郑州大学