AsLn2, a luciferin-related modified tripeptide from the bioluminescent earthworm Fridericia heliota

作者：Petushkov Valentin N; Dubinnyi Maxim A; Rodionova Natalja S; Nadezhdin Kirill D; Marques Simone M; Esteves da Silva Joaquim C G; Shimomura Osamu; Yampolsky Ilia V^*

来源：Tetrahedron Letters, 2014, 55(2): 463-465.

DOI：10.1016/j.tetlet.2013.11.061

• Bioluminescence
• Fridericia heliota
• Luciferin
• Modified peptide

AsLn2, an unusual modified peptide, was isolated from the bioluminescent earthworm Fridericia heliota (Enchytraeidae). Its structure, elucidated by NMR and mass spectrometry, includes residues of tyrosine, CompX (a novel tyrosine modification product, reported in the accompanying paper), and N(omega)-acylated lysine. Chromatography, UV, and H-1 NMR data imply a close structural similarity of AsLn2 with F. heliota luciferin. AsLn2 appears to be an intermediate or by-product in F. heliota luciferin biosynthesis.

• 出版日期2014-1-8