Musculoskeletal ultrasonography assists the diagnostic performance of the 2010 classification criteria for rheumatoid arthritis

作者:Kawashiri Shin ya*; Suzuki Takahisa; Okada Akitomo; Yamasaki Satoshi; Tamai Mami; Nakamura Hideki; Origuchi Tomoki; Mizokami Akinari; Uetani Masataka; Aoyagi Kiyoshi; Eguchi Katsumi; Kawakami Atsushi
来源:Modern Rheumatology, 2013, 23(1): 36-43.
DOI:10.1007/s10165-012-0628-7

摘要

We investigated whether musculoskeletal ultrasonography (MSKUS) assists the diagnostic performance of the 2010 rheumatoid arthritis (RA) classification criteria. %26lt;br%26gt;Sixty-nine early arthritis patients were consecutively enrolled. None of the patients had been treated. In MSKUS of bilateral wrist and finger joints from 22 sites, the findings obtained by gray-scale and power Doppler (PD) assessment were graded on a semiquantitative scale from 0 to 3. Plain magnetic resonance imaging (MRI) of both wrist and finger joints was also examined. Diagnosis of RA was defined by the initiation of disease-modifying antirheumatic drugs within the first 3 months. The diagnostic performance of the patients was evaluated at entry using 2010 RA classification criteria in conjunction with MSKUS. %26lt;br%26gt;The indispensable MSKUS finding for differentiating RA was the presence of a PD grade 2 or 3 that was superior to 2010 RA classification criteria or MRI-proven bone edema. We propose that the decision tree algorithm of 2010 RA classification criteria with PD grade 2 or 3 reveals the best discriminative ability. %26lt;br%26gt;MSKUS, especially with a strong PD signal, is very useful to assist the diagnostic performance of the 2010 RA classification criteria in the early recognition of RA.

  • 出版日期2013-1