A new indole alkaloid and anti-inflammatory constituents from Strychnos cathayensis

作者:Chen Jih Jung*; Luo Yn Ting; Hwang Tsong Long; Sung Ping Jyun; Wang Tai Chi; Chen Ih Sheng
来源:Chemistry and Biodiversity, 2008, 5(7): 1345-1352.
DOI:10.1002/cbdv.200890122

摘要

A new indole alkaloid, 11,12-dimethoxyhenningsamine (1), was isolated from the roots of Strychnos cathayensis, together with 19 known compounds. The structure of this new compound was determined through spectroscopic and mass-spectrometric analyses. Among the isolated compounds, 11-methoxy-henningsamine (3) and aesculetin dimethyl ether (4) exhibited potent inhibition (IC50 <5.5 mu g/ml) on superoxide-anion generation and elastase release by human neutrophils in response to fMet-Leu-Phe/ cytochalasin B.

  • 出版日期2008
  • 单位长春大学