科研之友
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摘要
Using water as a green reaction media, aldehydes or ketones react with 2-aminobenzohydrazide to give hydrazone firstly, and then a series of quinazolinone derivatives are obtained by the reaction of the hydrazone with another molecule of aldehyde or ketone catalyzed by 1 mol% Yb(OTf)(3). This method provides several advantages such as neutral conditions, high yields (80%similar to 94%), simple work-up and environmental benignity. The structures were established by spectroscopic data of IR, H-1 NMR and HRMS techniques.
- 出版日期2011-9
- 单位江苏师范大学
