A revised nomenclature for the human and rodent alpha-tubulin gene family

作者:Khodiyar Varsha K*; Maltais Lois J; Sneddon Katherine M B; Smith Jennifer R; Shimoyama Mary; Cabral Fernando; Dumontet Charles; Dutcher Susan K; Harvey Robert J; Lafanechere Laurence; Murray John M; Nogales Eva; Piquemal David; Stanchi Fabio; Povey Sue; Lovering Ruth C
来源:Genomics, 2007, 90(2): 285-289.
DOI:10.1016/j.ygeno.2007.04.008

摘要

\An essential component of micrombules, alpha-tubulin is also a multigene family in many species. An orthology-based nomenclature for this gene family has previously been difficult to assign due to incomplete genome builds and the high degree of sequence similarity between members of this family. Using the current genome builds, sequence analysis of human, mouse, and rat alpha-tubulin genes has enabled an updated nomenclature to be generated. This revised nomenclature provides a unified language for the discussion of these genes in mammalian species; it has been approved by the gene nomenclature committees of the three species and is supported by researchers in the field.

  • 出版日期2007-8
  • 单位中国地震局; 上海生物信息技术研究中心