Hyaluronic Acid Gel Distribution Pattern in Periocular Area With High-Resolution Ultrasound Imaging

作者：Goh Alice S^*; Kohn Jocelyne C; Rootman Daniel B; Lin Joseph L; Goldberg Robert A

来源：Aesthetic Surgery Journal, 2014, 34(4): 510-515.

DOI：10.1177/1090820X14528206

• hyaluronic acid
• high-resolution ultrasound
• filler
• periocular hollow
• ultrasound
• Belotero Balance
• Restylane-LT
• cosmetic medicine
• oculoplastics

Background: High-resolution ultrasound (HRUS) is a useful tool in defining anatomic and dynamic soft tissue relationships in the periocular area. It also allows visualization of hyaluronic acid (HA) gel within the soft tissue.
Objectives: The authors investigate the difference in the distribution pattern between 2 HA fillers in the periocular tissue using HRUS.
Methods: The charts of 10 patients who underwent periocular injection using HA gel filler and were subsequently examined with HRUS were reviewed. Half of the patients (n = 5) were treated with Restylane-L (Medicis Aesthetics, Inc, Scottsdale, Arizona) and the remaining 5 with Belotero Balance (Merz Aesthetics, Inc, San Mateo, California). Ultrasonographic evaluation (Logiq p6; GE Healthcare, Waukesha, Washington) was performed before and immediately after HA filler injection.
Results: The HA appears as a hypoechoic image within the soft tissue plane on HRUS. Restylane-L filler formed a localized hypoechoic image within the tissue, with some spread into bubbles or pearl-like configuration. Belotero Balance spread more widely into the tissue plane and diffused into an elongated or spindle-shaped hypoechoic image.
Conclusions: Our preliminary data suggest that HA gel fillers with differing production technologies show distinct spread and distribution patterns in the periocular tissues on HRUS examination.

• 出版日期2014-5