Aspergillus endocarditis: a review of the literature

作者：Kalokhe Ameeta S^*; Rouphael Nadine; El Chami Mikhael F; Workowski Kimberly A; Ganesh Geeta; Jacob Jesse T

来源：International Journal of Infectious Diseases, 2010, 14(12): E1040-E1047.

DOI：10.1016/j.ijid.2010.08.005

• Aspergillus
• Endocarditis
• Fungal
• Culture-negative endocarditis

We present a case of cardiac device-related Aspergillus endocarditis in a patient with a pacemaker and an allogeneic bone marrow transplant to segue into a review of the Aspergillus endocarditis literature. Aspergillus endocarditis should be suspected in patients with underlying immunosuppression, negative cultures, and a vegetation on echocardiography. Diagnosis ultimately requires confirmation by tissue histology and culture. The optimal treatment approach often requires aggressive surgical debridement in conjunction with prolonged antifungal therapy.

• 出版日期2010-12