An efficient and novel one-pot synthesis of 2,4,5-triaryl-1H-imidazoles catalyzed by UO2(NO3)(2)center dot 6H(2)O under heterogeneous conditions

作者：Satyanarayana Vardhineedi Sri Venkata; Sivakumar Amaravadi^*

来源：Chemical Papers, 2011, 65(4): 519-526.

DOI：10.2478/s11696-011-0028-z

• 2,4,5-triaryl-1H-imidazoles
• uranyl nitrate hexahydrate
• heterogeneous system
• antimicrobial activity
• antioxidant activity

An efficient, convenient, and novel one-pot method of 2,4,5-triaryl-1H-imidazoles synthesis using benzil, arene carbaldehydes, and ammonium acetate, catalyzed by uranyl nitrate hexahydrate [UO2(NO3)(2)center dot 6H(2)O] supported on acidic alumina and resulting in good to excellent yields under heterogeneous conditions, is reported. Formation of a reactants-catalyst complex was confirmed by UV-VIS spectral data. Antibacterial (MIC) and antioxidant activity of the synthesized compounds was also studied.

• 出版日期2011-8