Alum: An efficient catalyst for one-pot synthesis of alpha-aminophosphonates

作者：Sonar Swapnil S; Shelke Kiran F; Kakade Gopal K; Shingate Bapurao B; Shingare Murlidhar S^*

来源：Chinese Chemical Letters, 2009, 20(9): 1042-1046.

DOI：10.1016/j.cclet.2009.04.024

• Alum
• alpha-Aminophosphonates
• Aldehyde/ketone
• Amine
• Triethyl phosphite
• Solvent-free

Alum (KAl(SO(4))(2)center dot 12H(2)O) is an inexpensive, efficient, non-toxic and mild catalyst for the one-pot synthesis of alpha-aminophosphonates. A three component reaction of an aldehyde/ketone, an an-tine and triethyl phosphite was carried out under solvent-free conditions to afford the corresponding alpha-aminophosphonates in short reaction times and high yields with the green aspects by avoiding toxic catalysts and solvents.

• 出版日期2009-9