Hereditary Breast/Ovarian Cancer Syndrome A Primer for Obstetricians/Gynecologists

作者：Meaney Delman Dana^*; Bellcross Cecelia A

来源：Obstetrics and Gynecology Clinics of North America, 2013, 40(3): 475-+.

DOI：10.1016/j.ogc.2013.05.009

• BRCA1
• BRCA2
• Hereditary breast cancer
• Hereditary ovarian cancer
• Genetic testing
• Clinical management

An understanding of the diagnosis and clinical management of hereditary breast and ovarian cancer syndrome (HBOC) is essential for obstetricians/gynecologists. This article provides practical information regarding collecting a family history, cancer risk assessment and genetic testing, BRCA-associated cancer prognosis and treatment, screening recommendations, and prevention strategies. Through appropriate cancer risk assessment, women with BRCA1/2 mutations can be identified, and screening and prevention strategies can be used before a diagnosis of cancer occurs. Women's health providers with a strong working knowledge of HBOC are able to improve the quality of care for women and families impacted by BRCA1/2 mutations.

• 出版日期2013-9