An ESIPT-based fluorescent probe for sensitive detection of hydrazine in aqueous solution

作者:Zhou, Ji; Shi, Ruiyan; Liu, Jianxu; Wang, Rui; Xu, Yufang*; Qian, Xuhong
来源:Organic and Biomolecular Chemistry, 2015, 13(19): 5344-5348.
DOI:10.1039/c5ob00209e

摘要

A fluorescent probe for sensitive detection of hydrazine based on an ESIPT mechanism and a substitution-cyclization-elimination cascade was developed. After the addition of hydrazine, an approximately 50-fold enhancement in fluorescence intensity at 465 nm was observed and the subsequent decrease at 375 nm was observed in 10 min with a detection limit of 0.147 mu M. We also detected hydrazine in HeLa cells successfully.