High rate of lymphoma among a UK cohort of adolescents with vertically acquired HIV-1 infection transitioning to adult care in the era of antiretroviral therapy

作者：Eades Chris P^*; Herbert Sophie A; Edwards Simon G; Waters Laura J; Peake Tabitha; Miller Robert F; Jungmann Eva

来源：AIDS, 2016, 30(1): 153-156.

DOI：10.1097/QAD.0000000000000942

Among an inner London UK cohort of 147 adolescents transitioning from paediatric into adult care between 2007 and 2015, a new diagnosis of lymphoma was made in five patients; incidence rate = 0.425/100 person-years (95% confidence interval = 0.424-0.426). Previously described risk factors, including low nadir CD4(+) cell count and ongoing HIV-1 viraemia, appeared to be important. These data suggest that careful surveillance and a low threshold for investigating relevant symptoms continue to be essential for such patients.

• 出版日期2016-1-2