Body mass index and myocardium at risk in patients with acute coronary syndrome

作者：Arrebola Moreno A L^*; Marfil Alvarez R; Catena A; Garcia Retamero R; Arrebola J P; Melgares Moreno R; Ramirez Hernandez J A; Kaski J C

来源：Revista Clinica Espanola, 2014, 214(3): 113-120.

DOI：10.1016/j.rce.2013.12.004

• Obesity paradox
• BARI score
• Acute myocardial infarction
• Acute coronary syndrome

Background and objectives: Whilst traditional studies have shown that obese individuals are at a higher risk of cardiovascular events compared to lean subjects, recent studies in patients with acute myocardial infarction (AMI) have suggested that obesity may exert protective effects (the %26quot;obesity paradox%26quot;). We sought to assess the relationship between body mass index (BMI) and the BARI score (BARIsc), a validated tool used to assess myocardium at risk, in patients with acute coronary syndrome. %26lt;br%26gt;Patients and methods: Participants were 116 consecutive patients (mean age, 60.6 years; 97 men) with AM! (68 ST elevated myocardial infarction, STEMI; 48 non-ST elevated myocardial infarction, NSTEMI). Demographics, BMI, risk factors, biochemistry data, left ventricular function, angiographic data and the BARIsc were assessed in every patient. %26lt;br%26gt;Results: Multiple linear regression analyses showed that BMI significantly correlated with BARIsc; beta=.23, p%26lt; 0.02. This was found only in the overweight/obese patients, beta=.27, p%26lt; 0.01, but not in patients with normal BMIs, beta=0.08, p=0.71. %26lt;br%26gt;Conclusions: An increased body weight is associated with an increased area of myocardium at risk in patients with ACS.

• 出版日期2014-4