Adhesion Barrier of Methylcellulose Based Thermo-Responsive Sol-Gel

作者:Kim Jin; Cheon Seo Young; Shin Dong Il; Lee Chang Moon*; Lee Ki Young*
来源:Polymer-Korea, 2017, 41(2): 318-323.
DOI:10.7317/pk.2017.41.2.318

摘要

Thermo-responsive sol-gel was prepared from methylcellulose (MC) and xanthan gum (XT) for adhesion barrier. The prepared MC/XT sol-gel showed transition temperature and gelation around body temperature (37 degrees C) within 1 min. In vivo biocompatibility and biodegradability of the MC/XT sol-gel were validated by implantation of the gel in rats. Also, the MC/XT sol-gel was highly effective for the prevention of tissue and organ adhesion. Therefore, the MC/ XT sol-gel can be a good candidate material as a tissue adhesion barrier.

  • 出版日期2017-3

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