Autoimmune recurrent facial palsy and bilateral sudden sensorineural hearing loss following Ramsay Hunt-like syndrome

作者：Psillas George^*; Arnaoutoglou Marianthi; Gatsios Trifonas; Rizos Dimitris; Koutsouraki Efrosini; Vital Victor

来源：Auris Nasus Larynx, 2012, 39(2): 229-232.

DOI：10.1016/j.anl.2011.03.007

• Bilateral sudden sensorineural hearing loss
• Herpes simplex virus
• Viral reactivation
• Autoimmune diseases
• Facial palsy

Objective: To describe the first published case of recurrent facial nerve palsy associated with bilateral sudden sensorineural hearing loss of autoimmune origin. %26lt;br%26gt;Case report: A 33-year-old male presented with acute facial palsy on the left following a vesicular herpetic eruption in the external ear canal on the same side. Serologic measurements demonstrated an elevation of IgM antibodies against herpes simplex virus but not for varicellazoster virus, confirming a Ramsay Hunt-like syndrome due to herpes simplex virus. The following four months, the patient exhibited other three episodes of facial palsy, well responded to steroid treatment. During the clinical course, a sudden sensorineural hearing loss was also diagnosed, initially on the left side and then on both sides. The autoimmune markers such as the antinuclear antibody and the anti-gangliosides antibodies (anti-GMI, anti-GQ1b) were found positive. Despite steroid treatment, hearing did not show any improvement, remaining moderate on the right and severe on the left. %26lt;br%26gt;Conclusion: Recurrent facial nerve palsy and bilateral sudden sensorineural hearing loss could be the expression of autoimmune disturbances. The initial triggered factor could be the herpes simplex virus infection, such as a Ramsay Hunt-like syndrome.

• 出版日期2012-4