Spatiotemporal expression of a twist homolog in the leech Helobdella austinensis

作者:Kim Jin Se; Jimenez Brenda Irene Medina; Kwak Hee Jin; Park Soon Cheol; Xiao Ping; Wei**lat David A*; Cho Sung Jin*
来源:Development Genes and Evolution, 2017, 227(4): 245-252.
DOI:10.1007/s00427-017-0585-4

摘要

Genes of the twist family encode bHLH transcription factors known to be involved in the regulation and differentiation of early mesoderm. Here, we report our characterization of Hau-twist, a twist homolog from the leech Helobdella austinensis, a tractable lophotrochozoan representative. Hau-twist was expressed in segmental founder cells of the mesodermal lineage, in subsets of cells within the mesodermal lineage of the germinal plate, in circumferential muscle fibers of a provisional integument during segmentation and organogenesis stages and on the ventral side of the developing proboscis. Thus, consistent with other systems, our results suggest that twist gene of the leech Helobdella might function in mesoderm differentiation.

  • 出版日期2017-7