Antiulcer and antimicrobial activities of Stryphnodendron rotundifolium Mart.

作者：Galvao Rodrigues Fabiola Fernandes; Cabral Brisa do Svadesvich; Melo Coutinho Henrique Douglas; Herzog Cardoso Andre Luiz; Campos Adriana Rolim; Martins da Costa Jose Galberto

来源：Pharmacognosy Magazine, 2008, 4(15): 193-196.

• Stryphnodendron rotundifolium
• ethanolic extract
• antiulcer
• antimicrobial activity

The ethanolic extract of Stryphnodendron rotundifolium stem bark (EESR) was investigated for therapeutic properties using ethanol-induced ulceration in mice. Antimicrobial and preliminary phytochemical screening of the extract was also investigated. The extract (200-400 mg/kg p.o.) dose dependently reduced ethanol (0.2 mL/animal p.o.)-induced ulceration in mice. EESR showed antimicrobial activity against five bacterial species (Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Shigella flexineri, Staphylococcus epidermidis) but not against the fungi Aspergillus niger. The above results show that Stryphnodendron rotundifolium bark probably contains some active ingredients that could be developed for health problems as have been claimed by traditional popular use.

• 出版日期2008-9