Degree of External Genital Malformation at Birth in Children with a Disorder of Sex Development and Subsequent Caregiver Distress

作者：Wolfe Christensen Cortney^*; Fedele David A; Kirk Katherine; Phillips Timothy M; Mazur Tom; Mullins Larry L; Chernausek Steven D; Lakshmanan Yegappan; Wisniewski Amy B

来源：Journal of Urology, 2012, 188(4): 1596-1600.

DOI：10.1016/j.juro.2012.02.040

• disorders of sex development
• genitalia
• parent-child relations
• mental health

Purpose: We determined whether the degree of genital malformation at birth in children with a disorder of sex development is related to subsequent caregiver distress, specifically symptoms of depression and anxiety. Materials and %26lt;br%26gt;Methods: A total of 66 caregivers of children with disorders of sex development were recruited from 3 centers that specialize in disorders of sex development medicine. The caregivers completed the Beck Depression Inventory, 2nd Edition and the Beck Anxiety Inventory. The child%26apos;s Prader score at birth was determined by the child%26apos;s treating pediatric endocrinologist and/or pediatric urologist at each institution. %26lt;br%26gt;Results: Results from the current study revealed that for caregivers of male children, under masculinization of the child%26apos;s genitals at birth was significantly related to higher levels of subsequent caregiver depression. In contrast, over masculinization of the genitals of female children at birth was unrelated to caregiver depression or anxiety. %26lt;br%26gt;Conclusions: These findings suggest that caregivers of male children with disorders of sex development may be at increased risk for psychological distress and could benefit from family based psychosocial interventions.

• 出版日期2012-10