N-(Organylmethylidene)bis(chloromethylidene)thiomorpholin-4-amines and -selenomorpholin-4-amines

作者：Martynov A V; Makhaeva N A; Amosova S V^*

来源：Chemistry of Heterocyclic Compounds, 2013, 49(5): 797-801.

DOI：10.1007/s10593-013-1311-4

• aldehydes
• hydrazones
• selenomorpholin-4-amine
• thiomorpholin-4-amine

The reaction of (2E,6E)-bis(chloromethylidene)thiomorpholin-4-amine and -selenomorpholin-4-amine with propionaldehyde, benzaldehyde, or 4-pyridinecarbaldehyde in benzene in the presence of catalytic amounts of formic acid gave the corresponding hydrazones, the N-(organylmethylidene)-(2E,6E)bis-(chloromethylidene)thiomorpholin-4-amines and -selenomorpholin-4-amines, as trans isomers. The structure of the hydrazones was confirmed by H-1 and C-13 NMR, as well as 2D H-1-H-1 NOESY experiments.

• 出版日期2013-8