alpha,alpha '-Dihydroxyketone formation using aromatic and heteroaromatic aldehydes with evolved transketolase enzymes

作者：Galman James L; Steadman David; Bacon Sarah; Morris Phattara****; Smith Mark E B; Ward John M; Dalby Paul A; Hailes Helen C^*

来源：Chemical Communications, 2010, 46(40): 7608-7610.

DOI：10.1039/c0cc02911d

Transketolase mutants have been identified that accept aromatic acceptors with good stereoselectivities, in particular benzaldehyde for which the wild type enzyme showed no activity.

• 出版日期2010