Multifocal electroretinogram in normal emmetropic subjects: Correlation with optical coherence tomography

作者：Azad Rajvardhan; Ghatak Urmimala^*; Sharma Yog Raj; Chandra Parijat

来源：Indian Journal of Ophthalmology, 2012, 60(1): 49-52.

DOI：10.4103/0301-4738.91345

• Central macular thickness
• multifocal electroretinogram
• normative database
• optical coherence tomography

Aim of the Study: To establish the normative database for multifocal electroretinogram (mfERG) parameters in a normal emmetropic population. To correlate the data so obtained with the central macular thickness obtained using the optical coherence tomography (OCT) scan. Materials and Methods: mfERG data were obtained from 222 eyes of 111 emmetropic subjects. The amplitude (nv/deg(2)) and implicit times (ms) of the first-order kernel mfERG responses (N1, P1, and N2 waves) were obtained and grouped into five rings (Ring 1: Central 2 degrees, Ring 2: 2-5 degrees, Ring 3: 5-10 degrees, Ring 4: 10-15 degrees, Ring 5: > 15 degrees). The central macular thickness (CMT) was obtained using the macular thickness scan protocol of the OCT. Results: The mfERG data obtained were used to create a normative database. The amplitudes of the mfERG waves were maximum in the fovea and progressively decreased with increasing eccentricity (P = 0.0001). The latencies of the P1 and N2 waves were longest in the central ring and progressively shortened with eccentricity (P = 0.0001). No statistically significant correlations were observed between central ring 1 parameters and the CMT. Conclusion: This study establishes normative database for mfERG parameters in an emmetropic population. No statistically significant correlation was noted between CMT and mfERG parameters.

• 出版日期2012-2
• 单位河北医科大学