摘要

Background: Diagnostic and therapeutic studies using contrast agents are currently used frequently. Conflicting results have been present regarding the effect of these agents on thyroid function.
Aim: The aim of this study was to evaluate the effect of contrast media administrated during coronary angiography on thyroid function parameters.
Methods and results: Thyroid function parameters of 50 consecutive patients who underwent elective coronary angiography were studied before entering the study and I month after the procedure. The baseline mean TSH, FT4 and FT3 values were in the normal range in all patients before the procedure. However, one month after the procedure, the mean values of all thyroid function parameters decreased significantly (-0.73 +/- 1.65 mU/ml, p=0.003 for TSH; -0.28 +/- 0.56 pmol/l, p=0.001 for FT3; -0.07 +/- 0.20 pmol/l, p=0.024 for FT4).
Conclusion: Routine study of thyroid function tests in subjects with normal thyroid glands before coronary angiography is unnecessary.

  • 出版日期2012
  • 单位中国人民解放军军事医学科学院