Pharmacologic Issues of Antiretroviral Agents and Immunosuppressive Regimens in HIV-infected Solid Organ Transplant Recipients

作者：Primeggia Jennifer^*; Timpone Joseph G Jr; Kumar Princy N

来源：Infectious Disease Clinics of North America, 2013, 27(2): 473-+.

DOI：10.1016/j.idc.2013.02.011

• HIV
• Immunosuppression
• Organ transplantation
• Drug interactions

HIV-positive patients are now undergoing solid organ transplantation at increasing rates, with successful outcomes. Transplantation in this unique patient population presents new challenges in the postoperative management of both antiretroviral regimens and immunosuppressive regimens. This review highlights the drug-drug interactions between commonly used immunosuppressive and antiretroviral agents. As more antiretroviral regimens are cautiously initiated in the posttransplant period, further research is needed to identify drug-drug interactions to minimize toxicities and improve long-term survival and graft function.

• 出版日期2013-6