Weight-Loss Diet Alone or Combined with Progressive Resistance Training Induces Changes in Association between the Cardiometabolic Risk Profile and Abdominal Fat Depots

作者：Garcia Unciti Marisol; Izquierdo Mikel; Idoate Fernando; Gorostiaga Esteban; Grijalba Ana; Ortega Delgado Francisco; Martinez Labari Cristina; Moreno Navarrete Jose M; Forga Lluis; Manuel Fernandez Real Jose; Ibanez Javier^*

来源：Annals of Nutrition and Metabolism, 2012, 61(4): 296-304.

DOI：10.1159/000342467

• Hypocaloric diet
• Strength training
• Insulin resistance
• Lipid profile
• Visceral adipose tissue
• Subcutaneous adipose tissue
• Midthigh fat
• Adipocytokines

Background/Aims: A weight-loss diet alone or combined with a progressive resistance training program induced different adaptations on cardiometabolic risk, i.e. regional changes in visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) volume distribution patterns. We hypothesized that a heterogeneous adipose tissue metabolism may exist between visceral fat at different discal levels. Methods: Thirty-four obese women, aged 40-60 years, were randomized to three groups: a control group (n = 9), a diet group (WL; n = 12) with a caloric restriction of 500 kcal/day during 16 weeks, or a diet-plus-resistance-training group (WL+RT; n = 13) with the same caloric restriction and a 16-week resistance training of 2 sessions per week. Results: The association pattern between abdominal fat depots and glucose metabolism variables showed a change from the L4-L5 region (preintervention) to VAT L2-L3 and SAT L2-L3 in the WL and WL+RT groups, respectively. It is noteworthy that accumulation of fat in the midthigh was not characterized by a more favorable lipid profile or glucose metabolism. Conclusion: Our results reinforce the importance of considering L2-L3 images to predict insulin resistance after a weight-loss diet, alone or combined with resistance training.

• 出版日期2012