Adjuvant Therapy Trials

作者:Ursem Carling*; Van Loon Katherine; Venook Alan
来源:Cancer Journal, 2016, 22(3): 196-198.
DOI:10.1097/PPO.0000000000000188

摘要

In 2015, ramucirumab and TAS-102 became the 10th and 11th drugs approved by the Food and Drug administration for the treatment of patients with colorectal cancer, not counting leucovorin, and yet only 3 agents, 5-fluorouracil, capecitabine, and oxaliplatin, have proven benefit in adjuvant treatment. In fact, there have been no additions (and 1 subtraction levamisole) to our arsenal of therapies for patients with stages II and III colon cancer for more than a decade. How did we get here? Are we stuck? And how do we move forward?

  • 出版日期2016-6