An 8-year point-prevalence surveillance of healthcare-associated infections and antimicrobial use in a tertiary care teaching hospital in China

作者：Wu, Yi-Le; Yang, Xi-Yao^*; Pan, Meng-Shu; Li, Ruo-Jie; Hu, Xiao-Qian; Zhang, Jing-Jing; Yang, Li-Qi

来源：Epidemiology and Infection, 2019, 147: e31.

DOI：10.1017/S0950268818002856

• CLINICAL IMPACT
• RESISTANCE
• BURDEN

Healthcare-associated infections (HAIs) are a major worldwide public-health problem, but less data are available on the long-term trends of HAIs and antimicrobial use in Eastern China. This study describes the prevalence and long-term trends of HAIs and antimicrobial use in a tertiary care teaching hospital in Hefei, Anhui, China from 2010 to 2017 based on annual point-prevalence surveys. A total of 12 505 inpatients were included; 600 HAIs were recorded in 533 patients, with an overall prevalence of 4.26% and a frequency of 4.80%. No evidence was found for an increasing or decreasing trend in prevalence of HAI over 8 years (trend chi(2) = 2.15, P = 0.143). However, significant differences in prevalence of HAT were evident between the surveys (chi(2) = 21.14, P < 0.001). The intensive care unit had the high- est frequency of HAIs (24.36%) and respiratory tract infections accounted for 62.50% of all cases; Escherichia coli was the most common pathogen (16.67%). A 44.13% prevalence of anti- microbial use with a gradually decreasing trend over time was recorded. More attention should be paid to potential high-risk clinical departments and HAI types with further enhancement of rational antimicrobial use.

• 出版日期2019
• 单位安徽医科大学