Arrangement of a Nanostructure Array To Control Equilibrium and Nonequilibrium Transports of Macromolecules

作者：Yasui Takao^*; Kaji Noritada; Ogawa Ryo; Hashioka Shingi; Tokeshi Manabu; Horiike Yasuhiro; Baba Yoshinobu

来源：Nano Letters, 2015, 15(5): 3445-3451.

DOI：10.1021/acs.nanolett.5b00783

• Nonequilibrium transport
• macromolecules
• nanostructure array
• nanopillar

Exploiting the nonequilibrium transport of macromolecules makes it possible to increase the separation speed without any loss of separation resolution. Here we report the arrangement of a nanostructure array in micro-channels to control equilibrium and nonequilibrium transports of macromolecules. The direct observation and separation of macromolecules in the nanopillar array reported here are the first to reveal the nonequilibrium transport, which has a potential to overcome the intrinsic trade-off between the separation Speed and resolution.

• 出版日期2015-5