摘要

The nucleophilic reaction of 4'-aminobenzo-15-crown-5 and carbon disulphide in aqueous KOH afforded corresponding dithiocarbamate salt. Subsequent nucleophilic substitution reactions with sulfonamides aqueous NaOH provided benzo-15-crown-5-containing sulphonylthioureas. This novel, green method has the advantages of simple operation, high yields, easy product-isolation and environmental friendliness.

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