A linear mitochondrial genome of Cyclospora cayetanensis (Eimeriidae, Eucoccidiorida, Coccidiasina, Apicomplexa) suggests the ancestral start position within mitochondrial genomes of eimeriid coccidia

作者：Ogedengbe Mosun E; Qvarnstrom Yvonne; da Silva Alexandre J; Arrowood Michael J; Barta John R^*

来源：International Journal for Parasitology, 2015, 45(6): 361-365.

DOI：10.1016/j.ijpara.2015.02.006

• Mitochondrial genome
• Eimeriidae
• Cyclospora cayetanensis
• Apicomplexa
• Linear genome
• Genomics

The near complete mitochondria] genome for Cyclospora cayetanensis is 6184 bp in length with three protein-coding genes (Cox1, Cox3, CytB) and numerous lsrDNA and ssrDNA fragments. Gene arrangements were conserved with other coccidia in the Eimeriidae, but the C. cayetanensis mitochondrial genome is not circular-mapping. Terminal transferase tailing and nested PCR completed the 5'-terminus of the genome starting with a 21 bp A/T-only region that forms a potential stem-loop. Regions homologous to the C. cayetanensis mitochondrial genome 5'-terminus are found in all eimeriid mitochondrial genomes available and suggest this may be the ancestral start of eimeriid mitochondrial genomes.

• 出版日期2015-5